Male birth control drug 100% effective in mice, study shows. What about humans? – National

An experimental new drug that briefly blocks the male sperm is being hailed as a “game changer” in the search for an elusive birth control pill for men.

The drug was tested in pre-clinical trials in mice and showed 100 per cent effectiveness in preventing pregnancy, according to a peer-reviewed study published in Nature Communications on Tuesday.

Researchers at Cornell University injected the non-hormonal drug in male mice and among the 52 pairings that they tested, not a single female mouse got pregnant.

Read more:

Male birth control pill 99% effective on mice, human trials to start soon

Read next:

How rising food prices make eating healthy a big-time struggle for some Canadians

The drug works almost like an off-on switch as the sperm movement is blocked for up to 2.5 hours by using an inhibitor to target soluble adenylyl cyclase (sAC), which is essential for sperm motility and maturation. Motility then appeared to be restored the next day.

Story continues below advertisement

“So the idea is they take that pill about 30 minutes before they want to have intercourse and then their fertility is protected and then about 24 to 48 hours, their fertility comes back,” Dr. Melanie Balbach, a reproduction biologist at Weill Cornell Medicine and co-author of the study, told Global News.

It is an “on-demand” approach for male contraception that is not based on hormones and is “very different” than hormonal birth control pills for women, said Balbach.

Click to play video: 'New birth control option for men under development'

New birth control option for men under development

Women on birth control pills typically have to follow a regular multi-week regimen to prevent ovulation.

In the case of this drug being designed by Balbach and her colleagues, “it really hopefully can be taken as often as the men want to have intercourse,” she said.

After mice, the drug is now being tested in rabbits that are “more similar to humans,” said Balbach.

Story continues below advertisement

However, it might take two to three years before they can start clinical trials and see if the drug is safe and effective for humans, she said.

“We hope in about six to eight years, if everything goes well, it will come to (the) market.”

Click to play video: 'Some myths about female birth control'

Some myths about female birth control

So far, the main methods of contraception for men are condoms and vasectomy, but a number of drugs are being developed.

Women have several ways to control pregnancy such as pills, sponges, gels, IUDs, vaginal rings and diaphragms.

Read more:

Montreal man opens up about vasectomy at 27 in response to overturning of Roe v. Wade

Read next:

Sleep-deprived Calgarian still waiting for CPAP machine following massive recall

University of Ottawa professor Christabelle Sethna, an expert on the history of the birth control pill for women in Canada, said it’s “wonderful” to have more options “because women have been shouldering the burden of contraception for decades.”

Story continues below advertisement

She cautioned having a male birth control pill might mean condom use would drop, which is a concern for preventing sexually transmitted diseases (STDs) in the case of multiple partners.

If the drug does eventually make its way into the market after showing safety and efficacy, uptake will also be a challenge that will require social and cultural change, Sethna added.

“I think the marketing companies have a number of targets to hit if they want men to take up this pill,” she said.

&copy 2023 Global News, a division of Corus Entertainment Inc.

Source link

Denial of responsibility! galaxyconcerns is an automatic aggregator around the global media. All the content are available free on Internet. We have just arranged it in one platform for educational purpose only. In each content, the hyperlink to the primary source is specified. All trademarks belong to their rightful owners, all materials to their authors. If you are the owner of the content and do not want us to publish your materials on our website, please contact us by email – [email protected]. The content will be deleted within 24 hours.

Leave A Reply

Your email address will not be published.