Washington: US health officials would like to get the frequency of COVID-19 shots down to just one a year, and on Thursday they began discussing how to do that.
The message has come through loud and clear that Americans have already had enough of frequent COVID shots. Food and Drug Administration advisers are meeting to discuss issues such as which strains of coronavirus would be in an annual vaccine, and how they would be chosen.
Documents released earlier this week compared the America agency’s desired approach to the annual flu immunisation effort. As it stands now, anyone getting a COVID shot for the first time receives a vaccine designed in 2020, when the virus looked a lot different than it does today. The new strategy would require health officials to meet each year to review which strains of the virus should be included in the shots, just as they do with flu, for use each September ahead of the northern winter.
“I don’t think that we can chase after every new variant that comes along because the virus is changing so much,” said committee member Stanley Perlman, professor of immunology at the University of Iowa who sits on the FDA panel. “It makes it harder to convince people because if someone doesn’t want to get a shot every four months, the response might be ‘Well, I’m not going to get a shot at all’.”
Healthy adults would receive one COVID shot each autumn in the FDA plan, while children, the elderly and those with compromised immunity would receive two doses. Ad-hoc boosters could be used if a particularly vaccine-evasive strain of COVID arose.
Drugmakers Moderna, Pfizer and Novavax are scheduled to present clinical data on their shots. FDA staff and advisers discussed safety signals seen in one database that detected a higher risk of stroke among older adults who had received Pfizer’s updated booster. The signals were not picked up in other large databases, FDA officials said, but the agency would continue investigating the issue.
The FDA also said it planned to conduct an epidemiological study assessing the co-administration of flu and COVID vaccines before the 2023-2024 influenza season. Moderna and Pfizer are each developing shots that would target both viruses.
When the FDA’s advisory committee on vaccines last convened in June, they proposed the booster currently in use that targets Omicron variants that were prevalent at that time. The move raised the possibility of creating new boosters to combat each new variant.
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